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The Premier League has announced 40 new cases of Covid-19 among players and club staff - by far the highest figure recorded in a single week.
The results for December 28 to January 3 sawthe numberof positives surge from the previous high of 18, which was recordedthe week before.
In a statement, the Premier League said 28 tested positive from 1,311 tested between December 28 and December 31, with a further 12 positives from 984 players and staff who underwent tests from January 1 to January 3.
Although England has entered a national lockdown, professional sport is being allowed to carry on, unlike last season when the campaign went on hold for three months.
The latest figures from league chiefs follow the postponement of three matches last week due to coronavirus infections, with Fulham seeing their gamesagainst Tottenham and Burnley both called off, along with Manchester City's fixture at Everton.
Man City were, however, able to play their match against Chelsea days after their game against Everton was postponed, defeating Frank Lampard's side 3-1 on Sunday despite a number of positive tests among players and staff.
Despite this impact, the Premier League said it would press on with the season as intended. There have been calls from some in the game for a circuit break - a period in which clubs could look to get the virus under control.
West BrommanagerSam Allardycehas been among that group, saying last week:"I'm very concerned for myself and football in general."
The Premier League, however, said: "With low numbers of positive tests across the overwhelming majority of clubs, the league continues to have confidence in its Covid-19 protocols, fully backed by the government, to enable fixtures to be played as scheduled."