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Thiago Silva limped off the pitch with a suspected leg injury in the first half of Chelsea's clash with Tottenham.
Silva was unable to continue after receiving treatment from Chelsea's medical staff on the pitch, with Andreas Christensen subsequently brought on as his replacement.
The 36-year-old was making his 17th Premier League appearances for the Blues since joining the club on a free transfer, and his third under new head coach Thomas Tuchel.